Jaap J Plomp Selected Research

Miller Fisher Syndrome (Fisher Syndrome)

9/2008	C5 inhibitor rEV576 protects against neural injury in an in vitro mouse model of Miller Fisher syndrome.
5/2008	Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in a murine model.
1/2008	Anti-ganglioside antibodies and the presynaptic motor nerve terminal.
11/2005	Anti-disialosyl antibodies mediate selective neuronal or Schwann cell injury at mouse neuromuscular junctions.
6/2005	Concanavalin A inhibits pathophysiological effects of anti-ganglioside GQ1b antibodies at the mouse neuromuscular synapse.
11/2003	Calpain inhibitors protect against axonal degeneration in a model of anti-ganglioside antibody-mediated motor nerve terminal injury.
10/2003	Immunoglobulins inhibit pathophysiological effects of anti-GQ1b-positive sera at motor nerve terminals through inhibition of antibody binding.
8/2002	Complex gangliosides as autoantibody targets at the neuromuscular junction in Miller Fisher syndrome: a current perspective.
4/2002	Detection and prevalence of alpha-latrotoxin-like effects of serum from patients with Guillain-Barré syndrome.

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Jaap J Plomp Research Topics

Disease

14	Myasthenia Gravis 01/2022 - 08/2010
10	Muscle Weakness 01/2021 - 06/2005
9	Miller Fisher Syndrome (Fisher Syndrome) 09/2008 - 04/2002
8	Guillain-Barre Syndrome 03/2012 - 04/2002
6	Paralysis (Palsy) 04/2012 - 09/2004
4	Migraine Disorders (Migraine) 01/2010 - 06/2002
4	Ophthalmoplegia (External Ophthalmoplegia) 06/2005 - 04/2002
3	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2021 - 01/2016
3	Inflammation (Inflammations) 01/2021 - 01/2017
3	Ataxia (Dyssynergia) 12/2006 - 08/2002
2	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 01/2018
2	Muscular Dystrophies (Muscular Dystrophy) 01/2021 - 01/2006
2	Atherosclerosis 01/2017 - 01/2013
2	Emphysema 01/2017 - 01/2013
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2017 - 01/2013
2	Migraine with Aura (Familial Hemiplegic Migraine) 09/2010 - 03/2004
2	Peripheral Nervous System Diseases (PNS Diseases) 03/2009 - 11/2003
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021
1	Fibrosis (Cirrhosis) 01/2021
1	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 01/2019
1	Body Weight (Weight, Body) 01/2019
1	Shock 01/2019
1	Wounds and Injuries (Trauma) 07/2017
1	Cardiac Arrhythmias (Arrythmia) 07/2017
1	Weight Loss (Weight Reduction) 01/2017
1	Muscular Diseases (Myopathy) 01/2016
1	Pneumonia (Pneumonitis) 01/2013
1	Enteritis 03/2012
1	Necrosis 03/2012
1	Perinatal Death 10/2008
1	Respiratory Paralysis 05/2008
1	Lambert-Eaton Myasthenic Syndrome (Lambert-Eaton Syndrome) 04/2007
1	Nervous System Diseases (Neurological Disorders) 12/2006
1	Dystonia (Limb Dystonia) 12/2006
1	Epilepsy (Aura) 03/2004
1	Spider Bites (Spider Bite) 11/2003
1	Neuromuscular Diseases (Neuromuscular Disease) 10/2003

Drug/Important Bio-Agent (IBA)

17	AntibodiesIBA 01/2022 - 04/2002
15	AutoantibodiesIBA 01/2021 - 08/2002
12	GangliosidesIBA 03/2012 - 08/2002
10	Cholinergic ReceptorsIBA 01/2022 - 04/2012
9	Phosphotransferases (Kinase)IBA 01/2021 - 08/2010
8	Immunoglobulin G (IgG)IBA 01/2021 - 04/2012
8	muskIBA 01/2021 - 08/2010
6	Complement System Proteins (Complement)IBA 01/2018 - 11/2003
5	voltage-dependent calcium channel (P-Q type)IBA 09/2010 - 03/2004
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2012
4	DystrophinIBA 01/2021 - 01/2006
4	alpha-latrotoxinIBA 11/2005 - 04/2002
3	Neurotransmitter Agents (Neurotransmitter)IBA 01/2016 - 11/2005
2	Pharmaceutical PreparationsIBA 01/2021 - 01/2019
2	EpitopesIBA 01/2018 - 11/2005
2	LipopolysaccharidesIBA 01/2017 - 01/2013
2	SmokeIBA 01/2017 - 01/2013
2	Apolipoproteins E (ApoE)IBA 01/2017 - 01/2013
2	Acetylcholine (Acetylcholine Chloride)FDA Link 04/2012 - 04/2002
1	Simvastatin (Zocor)FDA LinkGeneric 01/2021
1	CholesterolIBA 01/2021
1	AgrinIBA 01/2019
1	neonatal Fc receptorIBA 01/2019
1	Sarcoglycans (beta Sarcoglycan)IBA 01/2019
1	Monoclonal AntibodiesIBA 01/2019
1	Fc Receptors (Fc Receptor)IBA 01/2018
1	Biological ProductsIBA 07/2017
1	Ion Channels (Ion Channel)IBA 07/2017
1	ManganeseIBA 01/2017
1	LDL Receptors (LDL Receptor)IBA 07/2013
1	Pancreatic Elastase (Elastase)IBA 01/2013
1	myasthenia gravis anti-skeletal muscle antibody (ASMA)IBA 12/2012
1	Immunoglobulins (Immunoglobulin)IBA 04/2012
1	Amantadine (Aman)FDA LinkGeneric 03/2012
1	Transforming Growth Factor beta2IBA 10/2008
1	eculizumab FDA Link 05/2008
1	calpain inhibitorsIBA 11/2003
1	Therapeutic UsesIBA 10/2003
1	Intravenous Immunoglobulins (IVIG)FDA Link 10/2003
1	GlycolipidsIBA 08/2002
1	OligosaccharidesIBA 08/2002
1	Calcium Channels (Calcium Channel)IBA 06/2002

Therapy/Procedure

2	Therapeutics 01/2019 - 05/2007
2	Intraperitoneal Injections 01/2017 - 05/2008
1	Injections 01/2019
1	Microelectrodes 01/2018
1	Intravenous Injections 05/2008